Hi Rose: I have to tell you that you have to hit rock bottom before you get up. I did, the last PV treatment almost killed me, I had a severe reaction to it and just barely made it before they coded me. From all the news I read it is your own body that fights back. Your brother has gone through a lot, but with your help, medical, and all our prayers he will return to good health. It is going to take time, a lot of it. JOan