efficacy and dependency rates with treatments

    • Anonymous
      March 14, 2010 at 11:40 am

      [I]from a Paris neuro hospital research:[/I]

      The common form of CIDP represented 51% of patients. We observed a high frequency of the sensory variant (35% of patients) and the rapid onset form (18%). A positive response to treatment was observed in 87% of patients, with a similar efficacy of prednisone and IVIg. However, in the long term, 40% of treated patients remained dependent on treatment. The IVIg dependency rate was higher than the prednisone or plasma exchange dependency rate (55%, 18%, and 23%, respectively; p = 0.0054). Severe handicap was observed in 24% of patients.

      [I]What interested me was the dependency rates. [/I]

    • Anonymous
      March 14, 2010 at 7:01 pm

      I’ve seen this before (or a similar study) and I spoke with Emily’s neuro about it. He said the steroid dependency drops because long term steroid use is not tolerated well. Dr’s take their patients off of steroids & plasma pheresis & put them on IVIG.

      What I decided to take from the article was “40% of treated patients remained dependent on treatment”. I read that as 60% of treated patients go off all treatments. But what can I say, I try to be a half glass full kind of gal.

      Where did you find this study?

    • Anonymous
      March 14, 2010 at 8:36 pm

      It does not surprise me at all. Many folks here are on some kind of long term IVIG use, of long term immunosuppresant, etc. Remember, the first word is Chronic, it doesn’t go away.

    • Anonymous
      March 14, 2010 at 8:41 pm

      [QUOTE=Emily’s_mom]
      Where did you find this study?[/QUOTE]

      [I]Published Online: 1 Mar 2010
      Correspondence to Karine Viala, Service de Neurophysiologie Clinique, Hôpital de la Salpêtrière, 47 bd de l’Hôpital 75651 Paris cedex 13, France. Tel: +33-1 42161931; Fax: +33-1 42162137; E-mail: [email]karine.viala@psl.aphp.fr[/email][/I]

    • Anonymous
      March 15, 2010 at 4:08 pm

      Do you have a link?

      Kelly

    • Anonymous
      March 15, 2010 at 4:15 pm

      [QUOTE=Emily’s_mom]Do you have a link? Kelly[/QUOTE]

      [I]check with the e-mail liaison.[/I]

    • Anonymous
      March 15, 2010 at 4:43 pm

      I just wanted to see if we had the same link for the article to see if there were 2 different studies done or if this info was re-released.

      That’s all.

      Honestly, I don’t really care enough to email anyone. It was just minor curiosity. But thanks anyway. 🙂

      Kelly