Reply To: galop syndrome

Gait disorder
Autoantibody
Late-age
Onset
Polyneuropathy

GALOP syndrome is considered a variant of the antisulfatide syndrome. Antisulfatide antibodies are associated with several subtypes of peripheral neuropathy. Predominantly sensory or sensorimotor axonal neuropathies are most common in this series, with the sensory component either small fiber or mixed fiber type. More info here:
https://www.researchgate.net/publication/14970315_Anti-sulfatide_antibodies_in_peripheral_neuropathy

According to what I’ve read and what Ausvoltz has said above – IVIg, SCIg, or cyclophosphamide, may produce improvement in weakness, sensory loss or gait disability. Corticosteroids (Prednisone, etc.) are doubtful to be of any aid, even when neuropathy is demyelinating.