galop syndrome

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    • #117717
      vgau863
      Participant

      Anyone familiar with this? Is the treatment protocols the same as CIDP?

    • #117718
      Ausvoltz
      Participant

      The only treatment that is the same is intravenous immunoglobulin. They use a chemotherapy drug cyclophosphamide to suppress the immune system which is in adifferent drug family that is used in CIDP
      Corticosteroids which are used in CIDP are unlikely to be of benefit people with Gallop syndrome.
      So it’s a yes no answer.

    • #117719
      Jim-LA
      Moderator

      Gait disorder
      Autoantibody
      Late-age
      Onset
      Polyneuropathy

      GALOP syndrome is considered a variant of the antisulfatide syndrome. Antisulfatide antibodies are associated with several subtypes of peripheral neuropathy. Predominantly sensory or sensorimotor axonal neuropathies are most common in this series, with the sensory component either small fiber or mixed fiber type. More info here:
      https://www.researchgate.net/publication/14970315_Anti-sulfatide_antibodies_in_peripheral_neuropathy

      According to what I’ve read and what Ausvoltz has said above – IVIg, SCIg, or cyclophosphamide, may produce improvement in weakness, sensory loss or gait disability. Corticosteroids (Prednisone, etc.) are doubtful to be of any aid, even when neuropathy is demyelinating.

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