galop syndrome
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Anyone familiar with this? Is the treatment protocols the same as CIDP?
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The only treatment that is the same is intravenous immunoglobulin. They use a chemotherapy drug cyclophosphamide to suppress the immune system which is in adifferent drug family that is used in CIDP
Corticosteroids which are used in CIDP are unlikely to be of benefit people with Gallop syndrome.
So it’s a yes no answer. -
Gait disorder
Autoantibody
Late-age
Onset
PolyneuropathyGALOP syndrome is considered a variant of the antisulfatide syndrome. Antisulfatide antibodies are associated with several subtypes of peripheral neuropathy. Predominantly sensory or sensorimotor axonal neuropathies are most common in this series, with the sensory component either small fiber or mixed fiber type. More info here:
https://www.researchgate.net/publication/14970315_Anti-sulfatide_antibodies_in_peripheral_neuropathyAccording to what I’ve read and what Ausvoltz has said above – IVIg, SCIg, or cyclophosphamide, may produce improvement in weakness, sensory loss or gait disability. Corticosteroids (Prednisone, etc.) are doubtful to be of any aid, even when neuropathy is demyelinating.
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