galop syndrome

    • September 12, 2020 at 3:20 pm

      Anyone familiar with this? Is the treatment protocols the same as CIDP?

    • T
        September 12, 2020 at 4:19 pm

        The only treatment that is the same is intravenous immunoglobulin. They use a chemotherapy drug cyclophosphamide to suppress the immune system which is in adifferent drug family that is used in CIDP
        Corticosteroids which are used in CIDP are unlikely to be of benefit people with Gallop syndrome.
        So it’s a yes no answer.

      • September 12, 2020 at 4:35 pm

        Gait disorder
        Autoantibody
        Late-age
        Onset
        Polyneuropathy

        GALOP syndrome is considered a variant of the antisulfatide syndrome. Antisulfatide antibodies are associated with several subtypes of peripheral neuropathy. Predominantly sensory or sensorimotor axonal neuropathies are most common in this series, with the sensory component either small fiber or mixed fiber type. More info here:
        https://www.researchgate.net/publication/14970315_Anti-sulfatide_antibodies_in_peripheral_neuropathy

        According to what I’ve read and what Ausvoltz has said above – IVIg, SCIg, or cyclophosphamide, may produce improvement in weakness, sensory loss or gait disability. Corticosteroids (Prednisone, etc.) are doubtful to be of any aid, even when neuropathy is demyelinating.