Reply To: CIDP cause – surgery & implants

April 5, 2020 at 9:10 pm

GBS/CIDP is an autoimmune system disorder where antibodies are triggered in response to an invading organism or antigen (often the Campylobacter bacteria) and the antibodies produced (Lymphocytes, B-cells, T-cells) that normally detect “self” are defective and don’t properly recognize “self”.

More likely might be an immune response to metal toxicity, if you have some sensitivity to metals and they were surgically implanted. Are you allergic to types of jewelry (silver, gold, aluminum, stainless steel, etc.)? Here is an article that may help explain the metal toxicity risk better:

Although rare, it is not impossible one could trigger an immune response from a surgical procedure. However, the chances that a TKR, surgery, a nerve block, or local anesthetic (lidocaine, etc.) would cause the immune system to respond with any such antibodies, or trigger a reoccurrence of GBS/CIDP, I think is quite slim. If it did, immunosuppressants (Prednisone, etc.) can be employed to reduce the immune response, but I would not think the risk warrants it.

Perhaps the surgery followed another event that triggered an immune response?