Does your pain get worse towards evening? Mine does, and I remember DocDavid saying his did. He suggested taking the drug not evenly throughout the day, but along a path similar to your pain course. For example, if you wake up with a tolerable pain level and don’t have an increase until say 3 pm, then take your first dose at about 1 pm and then evenly spaced until your normal bedtime. This idea works for me.