Reply To: CIDP and Gamunex-C Dosage

Good afternoon, as a patient with CIDP as well as an acute care clinical pharmacist we dose many drugs based on adjusted lean body weight vs. ideal body weight, or actual body weight.  It does however depend on the pharmacodynamics and pharmacokinetics of the drug including volume of distribution in various tissues and  fluids.  That being stated, adjusted lean body weight is for patients who have total body weight 30% or greater than their lean body weight or ideal body weight.  The difference between the two multiplied by 0.4 and added to the patient’s lean or ideal body weight. This is more a pharmacist and researcher type calculation and not necessarily common practice amongst physicians.