Reply To: how to know if ivig NOT working

There is no way to answer your question absolutely as CIDP/GBS varies so greatly between patients.

IVIg stops our autoimmune system from producing antibodies that can attack self. The effects usually last about 2 weeks. If you already have antibodies in your system that can attack self, they will continue to do so until they are depleted. We can speed up the depletion with Plasm Exchange (PE) but it won’t stop us from producing more bad antibodies and will nullify IVIg.

I suggest 2-4 PE’s before starting IVIg to help accelerate recovery and minimize nerve damage.