Reply To: Anti-MAG treatment update

Rituximab is considered to be one of the most promising drugs in the treatment of anti-MAG peripheral neuropathy. This drug is an antibody against a protein which is primarily found on the surface of B cells which, when attached, destroys the B cells. Because of its ability to suppress the immune system, it has been used to treat anti-MAG neuropathy in the hopes that it will destroy cells that would target necessary glycoproteins on the Schwann cells. Studies in patients has shown that most patients experience marked increase in sensory and motor abilities within the first few months of therapy.

I suggest you talk to your doctor and explore the possibility of using Rituxan. This is not a low cost infusion treatment and you will need to confirm coverage by your insurance company before beginning treatments.