Flu Vaccine Linked to GBS

    • Anonymous
      November 13, 2006 at 4:51 pm

      Released today:

      Nov. 13 (Bloomberg) — Vaccines against influenza that the
      U.S. government is pushing to cut annual deaths and prepare for a
      possible pandemic may be linked to slightly higher rates of a
      paralyzing nerve disorder, a study found.
      Patients with the disorder, called Guillain-Barre syndrome,
      were more likely to have been diagnosed in the seven weeks after
      vaccination than in a comparison period four to six months later,
      Canadian researchers said in today’s issue of the Archives of
      Internal Medicine.
      The results of the study are consistent with earlier
      research on flu vaccine, and won’t change federal
      recommendations, said Jeanne Santoli, a vaccination expert with
      the U.S. Centers for Disease Control and Prevention, in a
      teleconference today. Federal officials are encouraging the
      production and use of flu shots to cut an estimated 36,000 deaths
      and more than 200,000 hospitalizations each year from influenza.
      “The risk is real. You don’t want to have this blindside
      you,” said Canadian researcher David Juurlink, who led the
      study, in a telephone interview, “But the benefits of
      vaccination are really substantial.”
      Sanofi-Aventis SA, GlaxoSmithKline Plc, Novartis AG and
      MedImmune Inc. make flu vaccine for the U.S. market, based on
      strains that public-health officials identify each year as the
      most common currently circulating. The CDC has expanded its
      guidelines for flu vaccine in recent years, and the agency now
      recommends immunization for almost two-thirds of Americans.
      While the risk of Guillain-Barre is so small that rates of
      the disease didn’t increase when a vaccination program began in
      Ontario, patients should be informed, Juurlink said.

      Ontario Program

      Increasing flu vaccine use will also help the U.S. prepare
      for mass immunizations in the event of a worldwide outbreak of
      lethal flu, which government health officials have said is
      Ontario began a universal flu vaccination program in 2000
      after a severe outbreak the previous year overloaded hospitals
      with patients. The program also presented flu experts with a way
      to examine suspected complications of the vaccine, such as
      Concerns about the mysterious, paralyzing disorder, which is
      usually temporary, arose in 1976 during an outbreak of the so-
      called swine flu that U.S. health officials warned might cause a
      pandemic. While the pandemic never materialized, the link raised
      long-standing fears about the safety of flu vaccine.
      A 1998 study in the New England Journal of Medicine found
      that flu vaccination raised the risk of Guillain-Barre 70
      percent. However, a 2003 review of other studies by the U.S.
      Institute of Medicine, the agency that creates volunteer expert
      panels to advise the government on health issues, found no
      association between Guillian-Barre and seasonal flu vaccination.


      Juurlink, a researcher at Canada’s Institute of Clinical
      Evaluative Sciences in Toronto, and his team found 269 patients
      diagnosed from April 1992 through March 2004 who developed the
      nerve disease within a six-month period after vaccination.
      Patients were 45 percent more likely to develop the disease in
      the first two months after vaccination than in the fifth and
      sixth months, the researchers said.
      Ontario also had begun a large immunization program against
      pneumococcal disease, a bacterial infection, that may have been
      responsible for some complications, said David Fedson, a former
      vaccine developer and University of Virginia professor of
      medicine, in an e-mailed response to questions.
      “The association is there,” with flu vaccine, Fedson said,
      “but the increase in risk is very small.”

      Benefits, Risks

      Young children and people who are at least 65 years old are
      at highest risk of complications from flu vaccination. More
      studies in these age groups, along with teens and young adults,
      are needed to show the benefits of vaccination against potential
      risks, he said.
      “Only in this way can people balance the benefit and risks
      of vaccination,” he said.
      Juurlink said he would continue to recommend vaccination for
      his patients and family.
      “It’s a no-brainer,” he said. “Literally tens of
      thousands of Americans don’t get hospitalized or die each year
      because they’ve had flu vaccine, and to me it’s worth the trade-

    • Anonymous
      November 13, 2006 at 5:26 pm

      Thank you Brian.

    • November 14, 2006 at 12:19 pm

      For what it is worth: I attended the GBS/CIDP symposium in Phoenix 10 days ago. The question was asked of the medical panel (leading neurologists who specialize in GBS/CIDP) about taking the flu shot. The panel agreed unanimously that GBS/CIDP folk should take the shot. They said that any vacination using dead virus, germs whatever was ok for us.

      I have had CIDP 13 years and have taken the flu shot each year of this period and each of my 3 neurologists during this time period have said “You already have it and a flare up won’t kill you. Flu might well kill you. Get the shot.”

    • Anonymous
      November 14, 2006 at 2:20 pm


      there is a thread on the Main Forum called …. [B]My News About The Symposium …. [/B]the last number of posts discuss the flu vac option. If you havent read it, it may be of interest to you. There were a few people from the forum at the Symposium that did attend that session.
      Forgive me for being skeptical, I have slightly different views, but hey, we can all agree to disagree .. 😉 . I recall vividly a year and a half ago a neurologist telling me that once GBS had run its course, you were better … period. No residuals! No post GBS. Nothing. So much for being a specialist …