Cortisone reaction

I have a diagnosis of CIDP for some 4 years now, and currently have 2 grams of intravenous Cortisone infusions every 2 weeks as treatment (IVIG didn’t work).

I usually have this on the Monday, however on Thursday I seem to suffer some kind of reaction to the treatment, I feel tired and lacking energy, and my hands and feet become even more numb/insensitive; this lasts about 24 hours, then improves.

It seems like I suffer some kind of reaction to the cortisone some 3 to 4 days after treatment.

Does anyone else suffer this?

The doctors cannot explain it.

Thank you.