Reply To: Not sure if IVIg is working

The important thing is to monitor muscle strength closely. A persistent loss of strength is a key indicator of this disease. If he is experiencing progressive loss of strength (not due merely to short-term fatigue), it is an indication of demyelination. For some, IvIg may provide only temporary relief from the progression of the disease. In my case, two loading doses of IvIg failed to arrest the progression of the disease, so my primary treatment was switched to plasma exchange.