As a follow-up to my reply, I actually do agree, after re-thinking my post, with what Pam H. suggests regarding looking NOW for an alternative/supplemental treatment to IVIG. Since your wife’s symptoms have developed fairly quickly, it seems that she should also respond quickly to IVIG if that were going to be the tx that would do the trick. IV Solumedrol might be an alternative to bring up with the specialist? I know this is a successful protocol for some. For me, it was a disaster and hastened my exacerbation in a negative way, but I believe I was out of the ordinary on that. Solumedrol evidently has fewer long-term side effects that oral Prednisone, unless you are on it for a very long time. I was only on IV Solumedrol for about 2 months, and may have received a total of 25 grams over that time period.