An overlooked aspect for the ‘twitches’ could be

a calcium depletion. Many of the meds we take for the pain are noted to either deplete calcium or to reduce the ability to asorb it. Further there can be a tendency to not asorb or us magnesium which helps the calcium work.
Try an increased dose of calcium that has magnesium + Vitamin D in it to reduce the ‘twitches’ [easier to spell]. It doesn’t kick in right away, but usually within about 7-10 days you will find some improvement.
The nerves need that calcium too, to function well. Look up calcium and magnesium deficiencies + nerves and see what it all says. Very interesting stuff.
Hope this helps.