Reply To: Solumedrol treatment caused weakness?

November 27, 2016 at 9:37 am

It took me a few more minutes to recall this tidbit: Steroids can make Multi Focal Motor Neuropathy (MMN) worse.

“In a proportion of patients with MMN, steroids worsened weakness, sometimes dramatically.4,71 Surprisingly, plasma exchange is also ineffective in MMN and may result in clinical and electrophysiological worsening.72 This puzzling finding underscores the unique pathophysiology of MMN as an entity distinct from motor predominant GBS, or other variants of inflammatory neuropathy, and remains one of the interesting aspects of MMN yet to be elucidated.”


And, for another good discussion on CIDP from this website, go to:

Consult closely with your doctors, including seeking 2nd or 3rd opinions, to make sure you have an accurate diagnosis.