thinking aloud again!

Anonymous
July 29, 2007 at 9:59 pm

Lori,

I’m a little confused by your post – are you trying to say that Copaxone has doubled his level of IL2 in the past month?

I got it!!! I just did a search for IL2 + IL17. I wouldn’t have thought of it until I read your post.

Naive T-cells can differentitate into Th1, Th2, or Th17 cells. In the past few years there has been a “discovery” concerning th17 – it has been said in some of the medical literature that this is the cell that produces the cytokine (IL17) which initiates many models of autoimmunity.

My search resulted in this article:

IL-2 Antagonizes Th17 Differentiation
[url]http://stke.sciencemag.org/cgi/content/abstract/sigtrans;2007/379/tw103[/url]

So, taking this one step further, if IL2 reduces the production of IL17, and IL2 comes from Th1 cells, then raising Th1 can be an effective way of “controlling” autoimmunity.

This is important to me, because the literature for the product I give my daughter claims to increase the production of Th1 cells. At the time, I was worried by the risk of the unknown, but I was wondering along this line of thought if it would help. (and it seems to have done just that)

OK – I’ll admit, this is just a theory, but eventually, someone is going to figure this out!

Whatever your doing, Lori, keep it up – and keep us informed of Dell’s progress.

best wishes always,

cd