SCT? Is SCT = BMT, or not?

September 7, 2011 at 9:15 pm

[QUOTE=Billt]…absolute greatest distinction between a non-myeloablative SCT, like they are performing at Northwestern for autoimmune diseases, and a true bone marrow transplant (BMT) as performed on patients with diseases such as Acute Lymphocytic Leukemia is that a true bone marrow transplant involves the infusion of marrow cells harvested from a DONOR.[/QUOTE]

I agree with what I take to be one of your premises which is that a myeloablative BMT has far greater risks than a non-myelobalative BMT/SCT.

However, I do not agree with the non-referenced statement above.

Nor do I agree that a SCT is any less a ‘true’ bone marrow transplant.

Afterall, that was the point of this thead. The two are one and the same, in my opinion and according to some references.

For example, a Wikipedia article already referred to us to read by another member says-

“[I]…Of these, 28,901 (57%) were autologous and 21,516 (43%) were allogeneic (11,928 from family donors and 9,588 from unrelated donors).

The main indications for transplant were lymphoproliferative disorders (54.5%) and leukemias (33.8%), and the majority took place in either Europe (48%) or the Americas (36%).[3]

In 2009, according to the world marrow donor association, stem cell products provided for unrelated transplantation worldwide had increased to 15,399 (3,445 bone marrow donations, 8,162 peripheral blood stem cell donations, and 3,792 cord blood units).[4]…[/I]”

So, in fact, according to this article, Autologous and periperhal blood stem cell transplants constitute the largest percentage of Bone Marrow transplants discussed in the article.