Multifocal Motor Neuropathy

Hi Barry:

One of the hallmarks of multifocal motor neuropathy is the total lack of sensory symptoms or sensory loss. MMN does not not present with tingling, numbness, etc – It is purely motor weakness, and painless. It is also typically quite asymetric (one hand much weaker than the other, etc.) It sounds as if you have considerable sensory issues, and those were your first symptoms. There is a variant of CIDP called Lewis-Sumner Syndrome, or it is sometimes called MADSAN (multifocal acquired demyelinating sensory and motor neuropathy.) This variant is asymetric (multifocal), presents with sensory and motor impairment and conduction block, and will often present with only mildly elevated CSF protein.

Lewis-Sumner is my diagnosis, and my onset sounds similar to yours (insidious sensory symptoms starting in feet) The condition can develop into severe disability, as it has for me.

You may consider seeing a neuromuscular or peripheral nerve specialist at a teaching university to really confirm your diagnosis, as MMN has divergent treatment options from MADSAN.

Best regards,

Bill