MMN or Multi focal Motor Neuropathy

Anonymous
May 8, 2011 at 7:12 pm

There were several doctors who suggested I might have this condition. Here is what the NIH says about it

“[I]…Is there any treatment? Treatment for multifocal motor neuropathy varies. Some individuals experience only mild, modest symptoms and require no treatment. For others, treatment generally consists of intravenous immunoglobulin (IVIg) or immunosuppressive therapy with cyclophosphamide. …[/I]”

and, more from [url]http://neuromuscular.wustl.edu/antibody/motpn2.htm[/url]

“[I]…B. Electrodiagnostic Classification
Motor neuropathies can be initially subdivided on the basis of electrophysiologic data.

1) Patients with MMN have, by definition, focal block of nerve conduction along the course of motor, but not sensory, axons. Conduction block has been variably defined as a 15% to 50% reduction in the compound muscle action potential at proximal as compared with distal sites of stimulation….[/I]”

The NEUROMUSCULAR DISEASE CENTER Washington University, St. Louis, MO USA article goes on to explain,

“…Immune demyelinating Neuropathies. Although MMN and CIDP are both demyelinating neuropathies, the differences in their clinical, electrophysiological and immunologic features are more prominent than their similarities. MMN commonly presents with distal asymmetric weakness while in CIDP, proximal symmetric weakness is a more common finding. The remitting and relapsing course that may occur in CIDP is uncommon in the motor neuropathies. Patients with MMN rarely have significant sensory symptoms while in CIDP, sensory signs are the rule…”

For those of you not familiar with these two terms, here’s how I look at them:

Distal- means the furthest away from the body

Proximal- nearest the body, connects to the body.