It is a question of control

December 30, 2009 at 7:24 pm

If your husband’s CIDP is well controlled with IVIg every 6 to 8 weeks, then there is little reason to add methotrexate. The Peripheral Nerve Society suggests using either corticosteroids (e.g., prednisone) or IVIg as the first line treatment. If that treatment works, taper the dose or frequency to the lowest effective dose. If that dose is still high, a combination treatment, such adding an immunosuppressant, should be considered. A dose of about 0.5 g IVIg per kilogram of body weight at 6 to 8 week intervals would not be considered high. Even if he were getting 1 g/kg every 4 weeks, my impression is that most doctors familiar with CIDP would not consider that dose as “high.”

Godspeed in your treatment options,