As Gary points out, one of the interesting observations about the Forum is how individualized and unique each of our neuropathy experiences can be.
After reading the posts and thinking about it some more, I am leaning toward the conclusion that much of the “morning syndrome” is caused by the lack of circulation, and indeed I feel much better after walking around for a while and enjoying a cup of coffee.
Gary, I notice too that when I drive long distances, my numbness seems to flair up. I get to the point where I am not sure if I will be able to feel the pedals properly. And the stocking and glove feeling gets the feet.

Likely, even if there was increased attack of the nerves during the night, it would not be to the extent that we would notice the change overnight. Otherwise, the onset would be much much faster (almost to the point of being like GBS).

Thanks for the thoughts on this subject of night versus day.

Dawn…regarding Kevin’s ankle tightness…I had the same thing. I guess the Rituxan has helped me to experience improvement in my IgM MGUS, but I also went back to running again because of the ankle tightness. At one stage, I had real difficulty coming down the stairs in the morning. I figured that the workouts I was doing on the Elyptic Trainer were helping the legs but not the ankles. One of the nice simple gadgets they have at the Y where I am a member is a wooden wedge that you can stand on to stretch the achilles. It seems to work well. I hope Kevin can regain strength in his ankles.