Article on responders vs. non-responders

July 10, 2010 at 4:21 pm

My husband has symmetrical sensorimotor (as proved by the two EMG/NCS studies done 1-year apart), but Dr. Harati claimed (as opposed to our other doctors) that his was more sensory. Given that proclamation, I finally pulled up an article by Angelika F. Hahn, which states: “there are ‘responders’ and ‘non-responders’, and that the efficacy of IVIg for predominantly motor CIDP was … high … but that patients with sensory forms are less likely to respond.” That’s the first published information stating there actually may be a difference in response to therapy, and why. If Dr. Harati is really right, then my hopes for remission are dimmer than they were.

You say IVig did not work for you. So how long were you on it; what was your protocol? Again, my husband has been on an every 4-week regimen for over a year. He has maintained that he hasn’t experienced “any improvement;” I believe him, as I continue to witness his decline. I’ve read that lots of people have used steriods and other immunosuppresants — some with success, many with little to no change. Every time I read that, my heart breaks for all of you.

I sincerely wish you success with the stem cell transplant. When are you going for this procedure? Will you keep up and let me know how you’re doing?

Thank you for your input, and best of luck to you, too!
Frances, thewife