Reply To: IVIG stopped, UGH!

January 15, 2018 at 2:23 pm

Even if CIDP causes, or is suspected to have caused, elevated CPK levels I would want to know at least two things.

1. Which form is CPK is high?- CPK is made of three slightly different substances:
CPK-1 (also called CPK-BB) is found mostly in the brain and lungs
CPK-2 (also called CPK-MB) is found mostly in the heart
CPK-3 (also called CPK-MM) is found mostly in skeletal muscle

2. Why is the CPK high? That is, rather than accept it is due to CIDP I would discuss with my doctor testing to rule out all of the more common factors. Specifically, heart attack, statin meds, intense muscle workout, alcohol, viruses, hereditary conditions and certain autoimmune diseases that cause inflammation in the muscle such as polymyositis or dermatomyositis.