Reply To: Ivig vs. PE

I had two loading doses (5-day regimen) of IvIg, but my strength continued to decline. Then I was switched to PE. I had nine treatments over a three-week period. I started to improve (from complete paralysis below the neck) after about seven. I never had IvIg again. In recovery I was given prednisone and mycophenolate mofetil.

I believe that the PE treatments were the key, but it is impossible to prove anything from a single case. Maybe I would have recovered without it. But it is known from studies that PE generally leads to better recovery.