Reply To: Symptoms common?

January 18, 2017 at 7:05 pm

Explain your side effects and ask at your infusion center about slowing the rates. Your doctor has probably only prescribed the total dose, not the actual infusion rates. However, the Infusion Center should have the freedom to adjust the rates as needed.

Generally, for each brand and type of IVIG the manufacturer’s package insert discusses rates and when and how much to increase the rate.

For example from the Gammagard Prescribing Information sheet for Intravenous Administration for treatment of PI (primary immune defeciency)- 300 to 600 mg/kg every 3 to 4 weeks based on clinical response

0.5 mL/kg/hr (0.8 mg/kg/min) for 30 minutes

Increase every 30 minutes (if tolerated) up to 5 mL/kg/hr (8 mg/kg/min)

Note that the Caution “IF TOLERATED” is standard prescribing language.

See in the post above about an infusion taking 7 hours.

Usually Insurance obstacles can be overcome. If not, this website has a section on Denied treatments

the link: