Reply To: Solumedrol treatment caused weakness?

November 27, 2016 at 9:20 am

I never took long term steroids. I did have one set of 5 day tapered oral dose with no noticeable side effects.

An online review shows muscle weakness as a side effect. However it is difficult to correlate dosage and time to onset or degree of weakness.


Generic name: Methylprednisolone
Other trade names: Duralone®, Medralone®, Medrol®, M-Prednisol®
Other names: 6-Methylprednisolone, Methylprednisolone Acetate, Methylprednisolone Sodium Succinate

The following side effects are common (occurring in greater than 30%) for patients taking Solu-Medrol:

Increased appetite
Difficulty sleeping (insomnia)
Swelling in your ankles and feet (fluid retention)
Nausea, take with food
Muscle weakness
Impaired wound healing
Increased blood sugar levels.

The above data is from:

Generally speaking, there are certain criteria to diagnose CIDP. Dr. Lewis, a specialist, has an article in Medscape. These criteria also include ruling out other diseases. Dr. Lewis lists 27 of them under differential diagnoses.


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Good luck with your condition and if IVIG helps then, in the words of a Mayo Clinic Doctor, “you have your diagnosis.”