Reply To: Chronic Fatigue with IVIG Treatment

I’ve had the same problem, however, it has been relieved somewhat with increased IV fluids after the IVIG infusion and a different combination of pain reliefs beforehand. I tried Benadryl and Tylenol before infusion , which dos nothing. Then ibuprofen/ Claritin with the same results. I then tried Naproxen and Benadryl and that made the headaches at least manageable. The increase of IV fluids to 500ml after a slow infusion of IVIG helped with my flu like symptoms. I was finally able to feel somewhat human and get out of bed last month. It only took 6 months to get this one right. I would feel as though I had the flu. Another option would be IV steroids before your infusion. Talk to your care team. Good luck.