Reply To: my cousin diagnosed as CIDP (NF155 IgG4 positive)

February 18, 2016 at 3:29 pm

This form of CIDP is more resistant to traditional IVIg treatment. Plasma Exchange may be a better treatment option to keep the disease from doing much more damage. You may wish to look into treatments using Rituxan as this may offer better hope for recovery in your cousin’s case.

A technical discussion of the IG4 antibody can be found here:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959751

A recent summary:
http://www.practiceupdate.com/content/2015-top-stories-in-neurology-cidp-unresponsive-to-therapy/31536

If you can give us your city, we may be able to suggest some medical providers.