Reply To: IVIG dependent CIDP

jk
September 7, 2014 at 1:30 pm

Yes, I have heard of it.

“..it was explained to us…” and how much credibility do these explainers have?

Personally, I might consider myself IVIG dependent, if and only if, I have tried and failed (and have been given them by a neuromuscular CIDP specialist) all of these:

Pub Med Central Theraputic Advances in Neurological Disorders by Kenneth C. Gorson corresponding author
Department of Neurology, St. Elizabeth’s Medical Center, 736 Cambridge Street, Boston, MA 02135, USA
Nov 2012; 5(6): 359–373.

Table 5.

Therapy for chronic inflammatory demyelinating polyneuropathy.
Proven therapies from randomized controlled trials: Level I evidence [Ashman and Gronseth, 2012]
IVIg
Prednisone
Plasma exchange
Pulse oral dexamethasone

Therapies ineffective based upon randomized controlled trials: Level I evidence; These studies all had difficulties in trial design:
Azathioprine
Interferon B1a (Level II evidence)
Methotrexate

Therapies of unproven benefit but probably helpful as steroid sparing agents, based upon clinical experience, and > 1 case series: Level IV evidence
Cyclosporine A
Cyclophosphamide
Azathioprine

Other therapies of unproven benefit: Level IV evidence
Mycophenolate mofetil
Pulse weekly oral prednisolone
Pulse weekly oral dexamethasone
Pulse weekly intravenous methylprednisolone
Rituximab
Interferon alpha 2a
Etanercept
Tacrolimus
Alemtuzumab
Natalizumab
Hematopoietic stem cell transplantation end quote.

Finally, I suggest that your conclusion “… And if that’s the case then stem cell transplant won’t work.” is neither factually based nor a correct conclusion based solely on the presumption of being “ivig dependent.”